中国高校科技期刊研究会第9次会员代表大会在北京召开,中宣部出版局副局长张怀海、教育部科学技术与信息化司一级巡视员张国辉等领导出席会议并发表..
英文简介:Cancer, the second leading cause of death, is a heterogenous group of over 100 diseases. Cancer is characterized by disordered and deregulated cellular and stromal proliferation accompanied by reduced cell death with the ability to survive under stresses of nutrient and growth factor deprivation, hypoxia, and loss of cell-to-cell contacts. At the molecular level, cancer is a genetic disease that develops due to the accumulation of mutations over time in somatic cells. The phenotype includes genomic instability and chromosomal aneuploidy that allows for acceleration of genetic change. Malignant transformation and tumor progression of any cell requires immortalization, loss of checkpoint control, deregulation of growth, and survival. A tremendous amount has been learned about the numerous cellular and molecular genetic changes and the host-tumor interactions that accompany tumor development and progression. It is the goal of the field of Molecular Oncology to use this knowledge to understand cancer pathogenesis and drug action, as well as to develop more effective diagnostic and therapeutic strategies for cancer. This includes preventative strategies as well as approaches to treat metastases. With the availability of the human genome sequence and genomic and proteomic approaches, a wealth of tools and resources are generating even more information. The challenge will be to make biological sense out of the information, to develop appropriate models and hypotheses and to translate information for the clinicians and the benefit of their patients. Cancer Biology & Therapy aims to publish original research on the molecular basis of cancer, including articles with translational relevance to diagnosis or therapy. We will include timely reviews covering the broad scope of the journal. The journal will also publish op-ed pieces and meeting reports of interest. The goal is to foster communication and rapid exchange of information through timely publication of important results using traditional as well as electronic formats. The journal and the outstanding Editorial Board will strive to maintain the highest standards for excellence in all activities to generate a valuable resource.中文简介:(来自Google、百度翻译)癌症是死亡的第二大原因,是100多种疾病的异质群体。癌症的特征是细胞和基质增殖紊乱和失调,伴随着细胞死亡的减少,并且能够在营养和生长因子剥夺,缺氧和细胞间接触丧失的压力下生存。在分子水平上,癌症是一种遗传疾病,由于体细胞中随时间推移突变的积累而发展。表型包括基因组不稳定性和染色体非整倍性,可加速遗传变化。任何细胞的恶性转化和肿瘤进展都需要永生化,失去检查点控制,生长失调和存活。关于伴随肿瘤发展和进展的众多细胞和分子遗传变化以及宿主-肿瘤相互作用,已经了解了大量知识。分子肿瘤学领域的目标是利用这些知识来了解癌症的发病机理和药物作用,以及开发更有效的癌症诊断和治疗策略。这包括预防策略以及治疗转移的方法。随着人类基因组序列以及基因组和蛋白质组学方法的可用性,大量的工具和资源正在产生更多的信息。挑战将是从信息中获得生物学意义,开发适当的模型和假设,并为临床医生及其患者的利益翻译信息。癌症生物学和治疗旨在发表关于癌症分子基础的原创研究,包括与诊断或治疗相关的翻译文章。我们将包括涵盖期刊广泛范围的及时评论。该杂志还将发表专栏文章和感兴趣的会议报告。目标是通过使用传统和电子格式及时发布重要成果,促进沟通和快速信息交流。《日刊》和杰出的编辑委员会将努力在所有活动中保持最高的卓越标准,以产生宝贵的资源。
英文简介:Cancer, the second leading cause of death, is a heterogenous group of over 100 diseases. Cancer is characterized by disordered and deregulated cellular and stromal proliferation accompanied by reduced cell death with the ability to survive under stresses of nutrient and growth factor deprivation, hypoxia, and loss of cell-to-cell contacts. At the molecular level, cancer is a genetic disease that develops due to the accumulation of mutations over time in somatic cells. The phenotype includes genomic instability and chromosomal aneuploidy that allows for acceleration of genetic change. Malignant transformation and tumor progression of any cell requires immortalization, loss of checkpoint control, deregulation of growth, and survival. A tremendous amount has been learned about the numerous cellular and molecular genetic changes and the host-tumor interactions that accompany tumor development and progression. It is the goal of the field of Molecular Oncology to use this knowledge to understand cancer pathogenesis and drug action, as well as to develop more effective diagnostic and therapeutic strategies for cancer. This includes preventative strategies as well as approaches to treat metastases. With the availability of the human genome sequence and genomic and proteomic approaches, a wealth of tools and resources are generating even more information. The challenge will be to make biological sense out of the information, to develop appropriate models and hypotheses and to translate information for the clinicians and the benefit of their patients. Cancer Biology & Therapy aims to publish original research on the molecular basis of cancer, including articles with translational relevance to diagnosis or therapy. We will include timely reviews covering the broad scope of the journal. The journal will also publish op-ed pieces and meeting reports of interest. The goal is to foster communication and rapid exchange of information through timely publication of important results using traditional as well as electronic formats. The journal and the outstanding Editorial Board will strive to maintain the highest standards for excellence in all activities to generate a valuable resource.中文简介:(来自Google、百度翻译)癌症是死亡的第二大原因,是100多种疾病的异质群体。癌症的特征是细胞和基质增殖紊乱和失调,伴随着细胞死亡的减少,并且能够在营养和生长因子剥夺,缺氧和细胞间接触丧失的压力下生存。在分子水平上,癌症是一种遗传疾病,由于体细胞中随时间推移突变的积累而发展。表型包括基因组不稳定性和染色体非整倍性,可加速遗传变化。任何细胞的恶性转化和肿瘤进展都需要永生化,失去检查点控制,生长失调和存活。关于伴随肿瘤发展和进展的众多细胞和分子遗传变化以及宿主-肿瘤相互作用,已经了解了大量知识。分子肿瘤学领域的目标是利用这些知识来了解癌症的发病机理和药物作用,以及开发更有效的癌症诊断和治疗策略。这包括预防策略以及治疗转移的方法。随着人类基因组序列以及基因组和蛋白质组学方法的可用性,大量的工具和资源正在产生更多的信息。挑战将是从信息中获得生物学意义,开发适当的模型和假设,并为临床医生及其患者的利益翻译信息。癌症生物学和治疗旨在发表关于癌症分子基础的原创研究,包括与诊断或治疗相关的翻译文章。我们将包括涵盖期刊广泛范围的及时评论。该杂志还将发表专栏文章和感兴趣的会议报告。目标是通过使用传统和电子格式及时发布重要成果,促进沟通和快速信息交流。《日刊》和杰出的编辑委员会将努力在所有活动中保持最高的卓越标准,以产生宝贵的资源。
来稿要求:
论点新颖、论证严密、论据充足、文字精练。论文字数:5000字符-8000字符为宜,图表也要计算在内,不包括英文摘要关键词。
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